Dr. Chang, with a professional background as an engineer and physician-scientist, is the co-founder of several medical technology startups, where he has led early-stage research and development. Previously, Dr. Chang served as a postdoctoral and lecturer at Massachusetts Institute of Technology (“MIT”), where he oversaw interdisciplinary research teams and developed curriculum in cardiovascular physiology and medical technology. His academic research has focused on cardiac support devices and extracorporeal systems. He has authored 14 peer-reviewed publications and is a named inventor on multiple U.S. patents related to cardiovascular and extracorporeal technologies. Dr. Chang’s contributions have been recognized through numerous honors, including the Paul & Daisy Soros Fellowship, the Seidman Prize for Outstanding Thesis, and teaching awards from both Harvard Medical School and MIT. Since June 2025, Dr. Chang has served as the chief medical officer of MicroPort Scientific Corporation, the controlling shareholder of the Company, whose shares are listed on the Stock Exchange (stock code: 0853).

Dr. Chang obtained a bachelor’s degree and a master’s degree in mechanical engineering from Carnegie Mellon University in December 2013 and May 2014, respectively, graduating with University Honors and a minor in biomedical engineering. He obtained a Ph.D. in medical engineering and medical physics from the MIT in June 2018 and a M.D. from Harvard Medical School in May 2023, graduating magna cum laude. He completed his residency in Internal Medicine at Massachusetts General Hospital through the stanbury physician-scientist program in June 2025.